Jul 01, 1986· What is claimed is: 1. A strontium- 82/rubidium-82 generator having a support medium for the strontium-82 comprising a compound of the formula M 10 (PO 4) 6 (OH) 2,. where in M is calcium, strontium, barium, lead, iron, sodium, potassium, zinc, cadmium, magnesium, aluminum or a …
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training, and support services to the nuclear cardiology and nuclear medicine community. About CardioGen-82 CardioGen-82 is a closed system used to produce rubidium Rb 82 chloride injection for intravenous use. Rubidium Rb 82 chloride injection is a radioactive diagnostic agent indicated
CardioGen-82 | Cardiac PET Imaging. The Rubidium-82 generator, CardioGen-82, is a closed system that produces the radiotracer for intravenous administration. CardioGen-82 includes a self-contained cart that houses a shield for the generator, on-board support for electronics, and a waste container.
Objectives Published radiation dose estimates for Rubidium-82 vary widely, and no comprehensive study in man has yet been conducted. With the increasing use of Rb-82 PET for myocardial perfusion imaging, improved dosimetry information is needed for accurate risk assessment. The purpose of …
Classes and Support Groups Ask A Health Librarian Subscribe to eNewsletters ... Drug Notes Home: More Features • Printer-friendly version: Rubidium rb 82 (By injection) Rubidium Chloride Rb 82 (roo-BID-e-um KLOR-ide Rb 82) Used in adults to help diagnose heart disease during a procedure called a positron emission tomography (PET) scan ...
Rubidium-82 generator based on sodium nonatitanate support, and improved separation methods for the recovery of strontium-82 from irradiated targets ... The compositions also have a very low affinity for rubidium, making it an ideal material for use as a 82Rb generator. Sodium nonatitanate materials of this type both improve the recovery of ...
Apr 30, 2019· 2.1 Radiation Safety - Drug Handling. Rubidium Rb 82 is a radioactive drug and should be handled with appropriate safety measures to minimize radiation exposure during administration [see Warnings and Precautions (5.3]).. Use only additive-free 0.9% Sodium Chloride Injection USP to elute the generator [see Boxed Warning, Contraindications, Warnings and Precautions ()].
Generic Cardiogen-82 Availability. Cardiogen-82 is a brand name of rubidium chloride rb-82, approved by the FDA in the following formulation(s):. CARDIOGEN-82 (rubidium chloride rb-82 - injectable;injection) Manufacturer: BRACCO Approval date: December 29, 1989
Jul 27, 2011· Health care professionals should stop using CardioGen-82 for cardiac positron emission tomography (PET) scans, the FDA said. The manufacturer, Bracco Diagnostics Inc. is voluntarily recalling CardioGen-82, according to an FDA statement released Tuesday afternoon.. CardioGen-82 consists of a generator used at clinical sites to produce rubidium-82 chloride injection.
Rubidium-82 chloride(Rb-82) is a metallic element which has a number of radioactive isotopes.It is used mostly for myocardial perfusion imaging; which shows the functionality of the heart muscle. It also detects the perfusion defects due to myocardial infarction.
CardioGen-82 ® (Rubidium Rb 82 Generator) is a closed system used to produce rubidium Rb 82 chloride injection for intravenous administration. Rubidium Rb 82 chloride injection is indicated for Positron Emission Tomography (PET) imaging of the myocardium under rest or pharmacologic stress conditions to evaluate regional myocardial perfusion in adult patients with suspected or existing ...
Rubidium chloride has been used to study the transport of potassium ions in humans, since rubidium ions are not naturally found in the body and when present they are treated as if they were potassium. In a similar way, because it tends to collect inside cells, especially tumours, the radioactive isotope Rb-82 can be used to locate brain tumours.
A more accurate assessment of the ischemic burden in patients with intermediate pretest probability of CAD can support the clinical decision-making in treatment of CAD patients as a complementary tool to the invasive coronary angiography (CAG). Recently, several studies have proven Rubidium-82 ((82)Rb) PET's long-term prognostic value by a ...
Rubidium-82 chloride (Rb-82) (T 1/2 = 75 sec) is a chemical analog of Tl-201 chloride used for the assessment of coronary artery disease with PET. 19, 33 Rb-82 is produced as the daughter radionuclide of strontium-82 (Sr-82) eluted from a portable on-site generator renewed approximately monthly due to the physical half-life of Sr-82 (T 1/2 = 25 ...
The short half-life of 82 Rb means that it must be supplied to physicians in the form of a generator, where the parent 82 Sr (T 1/2 =25 days) is immobilized on a solid substrate or support and 82 Rb …
Apr 01, 2019· Use only additive free 0.9% Sodium Chloride Injection USP to elute the generator ; Use CardioGen-82 with a specific infusion system. The recommended adult (70 kg) dose of rubidium Rb 82 chloride injection is 1480 MBq (40 mCi), with a range of 1110-2220 MBq (30-60 mCi) infused intravenously at a rate of 50 mL/minute, not to exceed a total volume of 100 mL.
Sep 13, 2013· 82 Rb- PET demonstrated sensitivity and specificity of 90% and 88% for the detection of obstructive coronary disease on invasive coronary angiography (Fig. (Fig.1). 1). 82 Rb- PET was demonstrated to have superior accuracy in comparison with 99m Tc- SPECT with both ECG-gating and attenuation correction (Mc Ardle et al., 2012).
May 21, 2010· Rubidium (Rb-82), a nonreactor produced tracer, is believed to have superior accuracy compared to Tc-99m and Tl-201 SPECT, with 5-20 times lower radiation dose. In the U.S. Rb-82 generators have been FDA-approved since 1989 and are used increasingly for CAD diagnosis, but are still considered investigational in Canada.
Further data for naturally occuring isotopes of rubidium are listed above. This table gives information about some radiosotopes of rubidium, their masses, their half-lives, their modes of decay, their nuclear spins, and their nuclear magnetic moments.; Isotope Mass / Da Half-life Mode of decay
The SSS ratings for N-13 ammonia and Rb-82 PET were significantly different for two of the readers (p<0.001), with a trend towards significance for the third reader (p=0.16). There was complete agreement among 3 readers in 8/10 subjects with Rb-82 PET, compared to 2/10 for N-13 ammonia PET scans.
Rb-82 to decay to acceptable levels. After decay of Rb-82, cleanup should be done wearing impermeable gloves in case there are traces of Sr-82 that remain. If cleanup is necessary before the Rb-82 decay is complete, the local Radiation Safety Officer should be consulted for additional personal protection measures, which could include the
A9555 Rubidium rb-82, diagnostic, per study dose, up to 60 millicuries HCPCS Code A9555 The Healthcare Common Prodecure Coding System (HCPCS) is a collection of codes that represent procedures, supplies, products and services which may be provided to Medicare beneficiaries and to individuals enrolled in private
Bracco Diagnostics Inc. announced today the launch of a new Web site with content focused on the myocardial perfusion agent CardioGen-82. CardioGen-82 is used for cardiac PET (Positron Emission Tomography), a diagnostic procedure that detects coronary artery disease.
P/91/2009: European medicines agency decision of 18 May 2009 on the refusal of a product specific waiver for rubidium-82 (EMEA-000488-PIP01-08) in accordance with Regulation (EC) No 1901/2006 of the European Parliament a...
Nov 11, 2011· Support The Guardian Available for everyone, funded by readers ... For example, rubidium-82 is a radioactive isotope, which is particularly useful in …
Cesium, the most electropositive and least abundant of the five naturally occurring alkali metals, was discovered spectroscopically in 1860. The first cesium metal was produced in 1881. Because cesium is not mined domestically, the United States is completely dependent on imports. Historically, the most important use for cesium has been in research and development,
Aug 11, 2010· Rubidium-82 Position Emission Computed Tomography (PET) Versus Gated, Rest / Stress Technetium 99-m SPECT (PETvsSPECT) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators.
– Daily delivery Rubidium 82 removes the need for a fixed generator. – We securely deliver and are responsible for the entire Bracco CardioGen-82 infusion system. – Our Clinical Applications Specialists provide comprehensive training and support.
Rubidium-82 (82Rb) is a PET perfusion tracer produced from a strontium-82 (82Sr)/ Rb generator and is widely used in centers without immediate access to a cyclotron (9,11,13–16). Rubidium-82 PET MPI is highly speciﬁc and sensitive for the diagnosis of CAD (11,13,14,17–19). How-ever, data supporting the prognostic value of 82Rb PET
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